| Autor: |
Tzu-Sen Yang, Mao-Suan Huang, Mao-Sheng Wang, Ming-Hong Lin, Meng-Yuan Tsai, Pei-Yi Wang Wang |
| Předmět: |
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| Zdroj: |
Implant Dentistry; Aug2013, Vol. 22 Issue 4, p374-379, 6p |
| Abstrakt: |
Purpose: In this study, the electrical discharge machining (EDM) was formed on the surface of the Ti-6Al-4V (Ti64) specimen. Materials: The properties of adhesion and proliferation of MG-63 cells were evaluated the interactions between the EDM-treated layer and cells. Results: The incorporation of oxygen roughened the EDM-treated specimen surface on a microscale, where the nanoscale pores were superimposed. The EDM-treated layer, which can generate the thick anatase Ti02 on the Ti64 surface, afforded a cytocompatible environment. In cell culture, alkaline phosphatase activity and osteocalcin can be dramatically enhanced on the EDM-treated surfaces when compared with the untreated surface. In addition, the increase in peak currents to the EDM functionalization led to enhancement of multiple osteoblast functions. Conclusions: This study reveals that the chemistry and crystallinily of the EDM-treated layer played important roles in affecting osteoblastic responses to the specimens, which provided insight into the development of new biomedical implant surfaces. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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