Seroepidemiological Investigatio n of Lyme Disease and Human Granulocytic Anaplasmosis among People Living in Forest Areas of Eight Provinces in China.

Autor: HAO Qin, GENG Zhen, HOU Xue Xia, TIAN Zhen, YANG Xiu Jun, JIANG Wei Jia, SHI Yan, ZHAN Zhi Fei, LI Guo Hua, YU De Shan, WANG Hua Yong, XU Jian Guo, WAN Kang Lin
Předmět:
Zdroj: Biomedical & Environmental Sciences; Mar2013, Vol. 26 Issue 3, p185-189, 5p
Abstrakt: Objective Lyme disease and Human granulocytic anaplasmosis are tick-borne diseases caused by Borrelia burgdorferi and Anaplasma phagocytophilum respectively. We have investigated infection and co-infection of the two diseases in the population of forest areas of eight provinces in China by measuring seroprevalence of antibodies against B. burgdorferi and A. phagocytophilum. Methods Forest areas in 8 provinces were chosen for investigation using whole sampling and questionnaire survey methods. 3 669 serum samples from people in the forest areas were tested for the presence of antibodies by indirect immunofluorescent assay (IFA). Results Seroprevalence against B. burgdorferi was 3% to 15% and against A. phagocytophilum was 2% to 18% in the study sites in the 8 provinces in China. We also found co-infection of B. burgdorferi and A. phagocytophilum in 7 of the 8 provinces (the exception being the Miyun area in Beijing). The seroprevalence for both B. burgdorferi and A. phagocytophilum was significantly higher among people exposed to ticks than among people who were not exposed to ticks. Conclusion We conclude that both pathogens are endemic in the forest areas in the eight provinces, but the prevalence of B. burgdorferi and A. phagocytophilum differs between the provinces. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index