| Autor: |
LAITEERAPONG, Arunee, LOCHAIWATANA, Yossakit, HIRATA, Isao, OKAZAKI, Masayuki, MORI, Kenta, MURAKAMI, Shinya, POOLTHONG, Suchit |
| Předmět: |
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| Zdroj: |
Dental Materials Journal; Sep2012, Vol. 31 Issue 5, p772-778, 7p |
| Abstrakt: |
This study aimed to investigate the in vitro biological response of human dental pulp cells to glass ionomer cement (GIC, Fuji IX GP®) containing 2.5% magnesium carbonate apatite (MgCO3Ap). MgCO3Ap was synthesized by wet method and characterized using FT-IR, XPS, and SEM. Fuji IX GP® served as a control. Test and control cements were prepared by encapsulated mixing the powder with Fuji IX-liquid (P/L=3.6:1). Eluates from cements extracted by 1 mL culture medium were collected at day 1, 7 and 14, and used for WST-1 proliferation assay. For ALPase activity, cells were maintained with cements in transwells, harvested and enzyme activity was measured at day 1, 4, 7, 14, and 21. We found a higher cell proliferation and increased ALPase activity by pulp cells in the test group compared to the control. This suggests the potential of GIC containing this novel biological apatite as a restorative material for pulp-dentin regeneration. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
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