| Autor: |
Xiao-Tao FENG, Tian-Zhan WANG, Jing LENG, Yi CHEN, Ji-Bo Liu, Yi Liu, Wen-Jian WANG |
| Předmět: |
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| Zdroj: |
Bioscience, Biotechnology & Biochemistry; Jul2012, Vol. 76 Issue 7, p1356-1361, 6p |
| Abstrakt: |
The article offers information on a study aimed to determine the effect of palmitate, a saturated fatty acid, on glucose metabolism in C2C12 mouse myotubes. It indicates that palmitate decreases insulin-stimulated glucose uptake and consumption by downregulating the Src-mediated phosphorylation of Akt. This provides new insight into the molecular mechanisms of free fatty acid (FFA)-induced insulin resistance. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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