Discovery of Tofogliflozin,a Novel C-Arylglucoside with an O-SpiroketalRing System, as a Highly Selective Sodium Glucose Cotransporter 2(SGLT2) Inhibitor for the Treatment of Type 2 Diabetes.

Autor: Ohtake, Yoshihito, Sato, Tsutomu, Kobayashi, Takamitsu, Nishimoto, Masahiro, Taka, Naoki, Takano, Koji, Yamamoto, Keisuke, Ohmori, Masayuki, Yamaguchi, Marina, Takami, Kyoko, Yeu, Sang-Yong, Ahn, Koo-Hyeon, Matsuoka, Hiroharu, Morikawa, Kazumi, Suzuki, Masayuki, Hagita, Hitoshi, Ozawa, Kazuharu, Yamaguchi, Koji, Kato, Motohiro, Ikeda, Sachiya
Zdroj: Journal of Medicinal Chemistry; Sep2012, Vol. 55 Issue 17, p7828-7840, 13p
Databáze: Supplemental Index