| Abstrakt: |
In the last years the understanding of the genetic influence on mammary gland development and function received an increased attention, because the improvement of milk production does not have to compromise animal's health. The variations in milk production cannot be attributed just to one gene, because mammary gland secretor activity is controlled by a cascade of hormones, transcription factors, enzymes, which over the years were affected by mutations which are probably the cause of these variations. On of the key players in proliferation and secretor activity of mammary epithelial cells is growth honnone (Gil) and therefore is a valuable candidate gene marker for improving milk production in cattle and other species. The present work had as a goal to study of Gil gene Alu 1 polymorphism from exon 5. This polymorphism was studied Romanian Black and White breed (RBW), Holstein type, a high milk production cattle breed and a primitive breed with very low milk production, as is Romanian Grey Steppe breed (RGS). L allele, associated in many studies with higher milk production, had the frequency 1 in RBW-high milk production individuals group. in RBW-low milk production individuals and ROS the following frequencies were found: L-0,700; V=300 and L=0,812; V=188, respectively. The polymorphism of Gil in the two Ronianian cattle breeds is a part of a more complex study, which is trying to better explain the genetic basis of milk production variability in cattle and goats, by studying the polymorphism of several key genes involved in mammary gland function. [ABSTRACT FROM AUTHOR] |
