Rational Design of Phosphoinositide3-Kinase αInhibitors That Exhibit Selectivity over the Phosphoinositide 3-Kinaseβ Isoform.

Autor: Timothy P. Heffron, BinQing Wei, Alan Olivero, StevenT. Staben, Vickie Tsui, Steven Do, Jennafer Dotson, Adrian J. Folkes, Paul Goldsmith, Richard Goldsmith, Janet Gunzner, John Lesnick, Cristina Lewis, Simon Mathieu, Jim Nonomiya, Stephen Shuttleworth, Daniel P. Sutherlin, Nan Chi Wan, Shumei Wang, Christian Wiesmann
Zdroj: Journal of Medicinal Chemistry; Nov2011, Vol. 54 Issue 22, p7815-7833, 19p
Databáze: Supplemental Index