Stromal Cell-Derived Factor-1 Retention and Cardioprotection for Ischemic Myocardium.

Autor: Kanki, Sachiko, Segers, Vincent F.M., Wu, Weitao, Kakkar, Rahul, Gannon, Joseph, Sys, Stanislas U., Sandrasagra, Anthony, Lee, Richard T.
Předmět:
Zdroj: Circulation: Heart Failure; Jul2011, Vol. 4 Issue 4, p509-518, 10p
Abstrakt: The article presents information on a study which investigated cardioprotection with the use of therapeutic stromal cell-derived factor-1 (SDF-1) specifically for myocardial ischemia/reperfusion. Results showed that a single dose of protease-resistant SSDF-1 has proven a significant improvement in angiogenesis and ventricular condition despite the onset of ischemia. The results can reportedly be used as a clinical approach in preventing heart failure.
Databáze: Supplemental Index