Use of palivizumab and infection control measures to control an outbreak of respiratory syncytial virus in a neonatal intensive care unit confirmed by real-time polymerase chain reaction.

Autor: O’Connell, K., Boo, T.W., Keady, D., NiRiain, U., O’Donovan, D., Commane, M., Faherty, C., Cormican, M.
Zdroj: Journal of Hospital Infection; Apr2011, Vol. 77 Issue 4, p338-342, 5p
Abstrakt: Summary: Respiratory syncytial virus (RSV) is a potentially life-threatening infection in premature infants. We report an outbreak involving four infants in the neonatal intensive care unit (NICU) of our hospital that occurred in February 2010. RSV A infection was confirmed by real-time polymerase chain reaction. Palivizumab was administered to all infants in the NICU. There were no additional symptomatic cases and repeat RSV surveillance confirmed that there was no further cross-transmission within the unit. The outbreak highlighted the infection control challenge of very high bed occupancy in the unit and the usefulness of molecular methods in facilitating detection and management. [ABSTRACT FROM AUTHOR]
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