The expression of IL-1β TNF-α induced by PrP106-126 in microglia.

Autor: Yang Li-feng, Zhou Xiang-mei, Yang Jian-min, Yin Xiao-min, Zhao De-ming
Zdroj: Chinese Journal of Veterinary Science / Zhongguo Shouyi Xuebao; 2009, Vol. 29 Issue 11, p1429-1433, 5p, 2 Diagrams, 2 Charts, 2 Graphs
Abstrakt: The article reports on the effects of the activation of microglia in the Central Nervous System (CNS). The activation of microglia leads to increased regulation of cytokines interleukin (IL-1β), TNF-α at the messenger RNA and protein levels. The data indicated that macrophage in the CNS may play a role in the neurons' damaging process.
Databáze: Supplemental Index