Observations on a new collagen barrier membrane in 16 consecutively treated patients. Clinical and histological findings.

Autor:	Friedmann, Anton, Strietzel, Frank Peter, Maretzki, Burghard, Pitaru, Sandu, Bernimoulin, Jean-Pierre, Friedmann, A, Strietzel, F P, Maretzki, B, Pitaru, S, Bernimoulin, J P
Předmět:	BIOLOGICAL membranes COLLAGEN GUIDED bone regeneration WOUND healing HISTOPATHOLOGY THERAPEUTIC use of minerals BONE substitutes ALVEOLAR process BIOPSY BONE regeneration BONES COMPARATIVE studies CONNECTIVE tissues OPERATIVE dentistry SURGICAL flaps GINGIVAL hyperplasia DIGITAL image processing DENTAL implants JAW diseases LONGITUDINAL method RESEARCH methodology MEDICAL cooperation ARTIFICIAL membranes NONPARAMETRIC statistics PHOTOGRAPHY RESEARCH EVALUATION research TREATMENT effectiveness SURFACE properties SURGICAL wound dehiscence EQUIPMENT & supplies THERAPEUTICS
Zdroj:	Journal of Periodontology; Nov2001, Vol. 72 Issue 11, p1616-1623, 8p, 12 Color Photographs, 2 Charts
Abstrakt:	Background: Space-maintaining capacity, cell disclusive potential, and stability over time are crucial factors to achieving sufficient bone augmentation with membrane barriers. The case series presented here assessed a new collagen barrier used in bone augmentation. Clinically, the healing pattern, especially in cases of secondary healing, was studied.Methods: Soft tissue healing was documented by photographs, and the size of the dehiscences calculated by image analysis. The measurements were performed on digitized photographs. During reentry, barrier remnants were dissected and histologically evaluated.Results: The mean value for dehiscences was 35.5 mm2; all dehiscences healed within 4 weeks after the exposure became evident. The difference was statistically significant between the week 2 and week 6 visits (P = 0.008) for each previously exposed site. The histologic observation of barrier remnants revealed direct apposition of fibrous and bone tissues on the membrane surface.Conclusion: In cases of membrane exposure, gingival dehiscences always disappeared in the following weeks without affecting the healing process. Histologic results showed barrier stability over a 6-month period, promoting bone regeneration. [ABSTRACT FROM AUTHOR]
Databáze:	Supplemental Index
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