High prevalence of antimicrobial drug-resistant diarrheagenic Escherichia coli in asymptomatic children living in an urban slum.

Autor: Souza, Tamara B., Morais, Mauro B., Tahan, Soraia, Melli, Ligia C.F.L., Rodrigues, Mirian S.C., Scaletsky, Isabel C.A.
Předmět:
Zdroj: Journal of Infection; Oct2009, Vol. 59 Issue 4, p247-251, 5p
Abstrakt: Summary: Purpose: The aim of this study was to investigate the presence of diarrheagenic Escherichia coli and antibiotic resistance in asymptomatic school-age children living in an area with defective environmental sanitation, comparing with children registered at a private school, both in the city of Osasco, Brazil. Methods: Seventy-nine school-age children between 5 and 10 years living in a slum and 35 children who attended a private school of the same city were included in the study. Results: DEC was found in 58% of the children living in the slum and in 17% of the control group (P =0.001). Resistance to at least one antimicrobial drug was found in 65% of DEC strains; resistant to two or more antimicrobial drugs was found in 46% of strains. Conclusion: The high carriage status among the slum children point towards the widespread environment contamination in low socio-economic housing conditions, in conformance with the pediatric population at higher risk for developing DEC diarrhea. [Copyright &y& Elsevier]
Databáze: Supplemental Index