| Autor: |
Nakashima, Keisuke, Kobayashi, Takao, Yoshihara, Akihiro, Fujiwara, Jun, Miyazaki, Hideo, Kowashi, Yusuke |
| Předmět: |
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| Zdroj: |
Journal of Periodontology; Apr2005, Vol. 76 Issue 4, p582-589, 8p, 5 Charts, 3 Graphs |
| Abstrakt: |
Background: A Japanese population residing in the same area may be suitable for evaluation of the association among IgG subclass levels, smoking status, and periodontal disease due to similar racial and environmental factors, as these factors can interact to influence serum IgG subclass levels. The present cross sectional investigation attempted to examine the influence of serum IgG subclass levels and smoking status on periodontal condition in a population of elderly Japanese subjects. Methods: Elderly individuals (N = 451, age, 71 years) residing in Niigata City, Japan participated in the present study. Clinical evaluations, which consisted of probing depth (PD), clinical attachment level (CAL), bleeding on probing (BOP), and calculus, and serological determinations including serum IgG subclass levels and anti-Porphyromonas gingivalis fimbriae IgG subclass titers were conducted. All participants were asked to complete questionnaires regarding smoking status and were then divided into one of three groups: never smoker, former smoker, or current smoker. Results: Distributions of the number of teeth did not differ significantly across the groups. The proportion of sites with CAL ≥4 mm (%CAL4) in current smokers was significantly higher in comparison with never smokers. Multiple linear regression analysis revealed that %CAL4 was influenced by number of teeth, serum IgG2 levels, gender, and smoking status (R² = 0.253, P <0.001). The effect of lgG2 was greater than that of smoking status. Distribution of IgG2 was not significantly different across the three groups. Conclusion: These data indicate that serum IgG2 levels influences periodontal conditions in an elderly Japanese population independent of smoking status. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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