Androgen Deprivation Induces Selective Outgrowth of Aggressive Hormone-Refractory Prostate Cancer Clones Expressing Distinct Cellular and Molecular Properties Not Present in Parental Androgen...

Autor: Cho-Lea Tso, McBride, William H., Jirong Sun, Patel, Belur, Ke-Hung Tsui, Paik, Sun H., Gitlitz, Barbara, Caliliw, Randy, van Ophoven, Arndt, Wu, Lily, deKemion, Jean, Belldegrun, Arie
Předmět:
Zdroj: Cancer Journal; Jul/Aug2000, Vol. 6 Issue 4, p220, 14p, 3 Color Photographs, 3 Black and White Photographs, 7 Graphs
Abstrakt: Examines the pathways of prostate cancer (CaP) cell growth under an androgen deprived condition in the United States. Association of hormonal therapy following first-line treatment failure with the selection of androgen-independent (AI) cell lines; Development of hormone-refractory disease despite androgen ablation; Cellular properties of AI variants.
Databáze: Supplemental Index