| Autor: |
Roche, Nicolas, Dalmay, François, Perez, Thierry, Kuntz, Claude, Vergnenègre, Alain, Neukirch, Françoise, Giordanella, Jean-Pierre, Huchon, Gérard |
| Zdroj: |
Respiratory Medicine; Nov2008, Vol. 102 Issue 11, p1568-1574, 7p |
| Abstrakt: |
Summary: Little is known on the long-term validity of reference equations used in the calculation of FEV1 and FEV1/FVC predicted values. This survey assessed the prevalence of chronic airflow obstruction in a population-based sample and how it is influenced by: (i) the definition of airflow obstruction; and (ii) equations used to calculate predicted values. Subjects aged 45 or more were recruited in health prevention centers, performed spirometry and fulfilled a standardized ECRHS-derived questionnaire. Previously diagnosed cases and risk factors were identified. Prevalence of airflow obstruction was calculated using: (i) ATS-GOLD definition (FEV1/FVC<0.70); and (ii) ERS definition (FEV1/FVC1. Prevalence and severity of chronic airflow obstruction are influenced not only by the definition used but also by equations used to calculate predicted FEV1/FVC and FEV1 values. These equations likely need to be periodically revised. [Copyright &y& Elsevier] |
| Databáze: |
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