Discovery of 3-{5-[(6-Amino-1H-pyrazolo[3,4-b]pyridine-3-yl)methoxy]-2-chlorophenoxy}-5-chlorobenzonitrile (MK-4965): A Potent, Orally Bioavailable HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor with Improved Potency against Key Mutant Viruses.
| Autor: | Thomas J. Tucker, John T. Sisko, Robert M. Tynebor, Theresa M. Williams, Peter J. Felock, Jessica A. Flynn, Ming-Tain Lai, Yuexia Liang, Georgia McGaughey, Meiquing Liu, Mike Miller, Gregory Moyer, Vandna Munshi, Rebecca Perlow-Poehnelt, Sridhar Prasad, John C. Reid, Rosa Sanchez, Maricel Torrent, Joseph P. Vacca, Bang-Lin Wan |
|---|---|
| Zdroj: | Journal of Medicinal Chemistry; Oct2008, Vol. 51 Issue 20, p6503-6511, 9p |
| Databáze: | Supplemental Index |
| Externí odkaz: |
|