| Autor: |
Brady, L. W., Heilmann, H. -P., Molls, M., Nieder, C., Constine, Louis S., Marks, Lawrence B., Okunieff, Paul, Rubin, Philip |
| Zdroj: |
Late Effects of Cancer Treatment on Normal Tissues; 2008, p99-107, 9p |
| Abstrakt: |
Philosophically, the TNM Cancer Classification is based on the premise that all malignant tumors have a similar life cycle. Cancers originate in a normal tissue, then spread regionally into lymph nodes and then to systematic distant sites hematogenously. In a parallel fashion, the conceptual design of a normal tissue TNM classification is based on a similarity of normal tissue injury following multimodal cancer treatment which is often greatest in the structure/organ of cancer origin and decreases in neighboring normal tissues. There may be a generalized or systemic toxicity. NT = The normal Tissue, anatomic structure, organ in which the cancer arose and spreads initially. NN = Neighboring or surrounding normal tissues or organs, viscera that are not involved by the tumor but in the regional nodal drainage zone. NM = SysteMic effects that are generalized and include hematologic, hepatic toxicity, weight loss. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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