| Autor: |
Bernard, A., Griffiths, B., Noé, W., Wurm, F., Fontana, Ombretta, Covini, Nevie, Pighini, Monica, Carpani, Daniela, Buono, Pasqualina, Soria, Marco R., Monaco, Lucia |
| Zdroj: |
Animal Cell Technology: Products from Cells, Cells as Products; 2000, p245-249, 5p |
| Abstrakt: |
The enzyme CMP-N-acetylneuraminic acid hydroxylase (CNAH) is responsible for the conversion of N-acetylneuraminic acid (NeuAc) into N-glycolylneuraminic acid (NeuGc). Incorporation of NeuGc residues into glycan chains of recombinant glycoproteins of therapeutic interest is not desirable, since NeuGc is potentially antigenic in man. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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