| Autor: |
Walker, John M., Double, John A., Thompson, Michael J., Naasani, Imad, Yamori, Takao, Tsuruo, Takashi |
| Zdroj: |
Telomeres & Telomerase; 2002, p197-207, 11p |
| Abstrakt: |
Modern biology provides a plethora of experimental evidence that points to the chaotic and heterogenous nature of cancer, making it necessary to tackle each type of cancer as a unique problem in terms of treatment. The existence of a labyrinth of multiple backup networks for every biological event in the living cell, from membrane receptors and signal transduction proteins to cell cycle systems and DNA/RNA processing machinery, performs as a vicious snare when it comes to the treatment of cancer. Alternatively, the huge number of chemotherapeutic options available today, with all of their known and unknown pharmacological modes, presents another sort of chaos and heterogeneity. Taken together, the achievement of improved cancer therapy would be easier if we applied our modern knowledge of informatic sciences as a means of managing and matching the two sources of heterogeneity or chaos, i.e., cancer and chemotherapy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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