Abstrakt: |
With the advent of nonradioactive probes during the past decade, in situ hybridization has become an immensely valuable tool in the hands of: 1.Developmental biologists and cell biologists for the detection of mRNA in cells and tissue sections (1-7),2.Virologists for detection of viral DNA and RNA (8), and3.Molecular cytogeneticists in detecting chromosome aberrations in interphase cells (Interphase Cytogenetics, especially Cancer Genetics, 9-11), sex determination (12,13), and gene mapping by nonisotopic in situ hybridization (NISH, 14,15). [ABSTRACT FROM AUTHOR] |