| Autor: |
Walker, John M., Bradley, Paul, Desai, Mohamed A. |
| Zdroj: |
Downstream Processing of Proteins; 2000, p141-160, 20p |
| Abstrakt: |
High-performance liquid chromatography (HPLC) was introduced commercially in the 1960s for the analysis of small molecules. The use of HPLC for the analysis and purification of macromolecules is a fairly recent development; traditional matrices did not provide the mechanical strength that was required for such an application. More recently, the introduction of semirigid (polystyrene) and rigid (silica) stationary phases has allowed macroporous matrices to be developed with sufficient mechanical strength to allow the use of high flow rates. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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