| Autor: |
Walker, John M., Brown, S. Moira, MacLean, Alasdair R., Bloom, David C. |
| Zdroj: |
Herpes Simplex Virus Protocols; 1998, p369-386, 18p |
| Abstrakt: |
A number of aspects of the natural biology of herpes simplex virus (HSV) make it an attractive candidate for a vector to express foreign genes within the nervous system. Some of the advantages of an HSV vector are 1Establishment of a life-long latent infection within peripheral and central nervous system neurons (for a review, see ref,1);2Latent HSV genomes exist as multiple episomal copies/neuron and integration is not known to occur (2), and3.Nonreplicating HSV recombinants can establish a latent infection efficiently (3) [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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