| Autor: |
Jarm, Tomaz, Kramar, Peter, Zupanic, Anze, Zywietz, Tosja K., Fischer, R. |
| Zdroj: |
11th Mediterranean Conference on Medical & Biomedical Engineering & Computing 2007; 2007, p22-25, 4p |
| Abstrakt: |
Drugs in general have the ability to cause delay of cardiac repolarization which can be measured as prolongation of the QT-interval in the ECG. A delay in cardiac repolarization can lead to so called Torsade de Pointes (TdP) and ventricular tachycardia, eventually leading to sudden cardiac death. All drugs must be therefore evaluated for their potential to delay cardiac repolarization in clinical trials. However, measuring the QT-interval with the required statistical accuracy is difficult. We have therefore developed a solution based on our intelligent analysis algorithm, which allows managing and analyzing the results of QT/QTc studies centrally, with an efficient mechanism to proof results by a confirming cardiologist. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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