Autor: |
Walker, John M., English, Lisa Bellavance, Rossé, Gérard, Neidig, Peter, Schröder, Harald |
Zdroj: |
Combinatorial Library; 2002, p123-139, 17p |
Abstrakt: |
The purity control and the structure verification of compound collections from automated synthesis and combinatorial chemistry play an essential role in the success of medicinal chemistry programs. High performance liquid chromatography (HPLC), mass spectrometry (MS), and liquid chromatographymass spectrometry (LC-MS) techniques are generally accepted as the most appropriate means of characterization (1,2). While these analytical methods are fast and easy to automate, they do not provide sufficient structural and quantitative data about the desired products. [ABSTRACT FROM AUTHOR] |
Databáze: |
Supplemental Index |
Externí odkaz: |
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