Camptothecins in the Treatment of Lung Cancer.

Autor: Teicher, Beverly A., Adams, Val R., Burke, Thomas G., Kumar, Pankaj, Haigentz, Missak, Gomez, Jorge, Perez-Soler, Roman
Zdroj: Camptothecins in Cancer Therapy; 2005, p369-419, 51p
Abstrakt: Since 1987 lung cancer has been the leading cause of cancer death in both men and women. In 2003 an estimated 171,900 new cases of lung cancer were diagnosed in the United States, and an estimated 157,200 deaths occurred from the disease. The incidence rate of lung cancer is declining in men, from a high of 102.1 per 100,000 in 1984 to 81.1 per 100,000 in 1999. In the late 1990s the incidence of lung cancer seen in women, which had been steadily rising, leveled off to the current incidence rate of 52.4 per 100,000. Overall, the 1-year survival rates for lung cancer have increased from 34% in 1975 to 42% in 1998, mainly because of improvements in surgical techniques. However, the 5-year relative survival rate for all stages is only 15% (1). [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index