| Autor: |
Jee, Govind, Grimm, Bernhard, Porra, Robert J., Rüdiger, Wolfhart, Scheer, Hugo, Brandis, Alexander S., Salomon, Yoram, Scherz, Avigdor |
| Zdroj: |
Chlorophylls & Bacteriochlorophylls; 2006, p485-494, 10p |
| Abstrakt: |
Recent progress in the bioproduction and chemical manipulation of bacteriochlorophyll (BChl) a has opened the way for utilization of highly potent sensitizers in photodynamic therapy. Although less stable than their chlorin analogues in their native form, BChl derivatives provide a superior optical and biophysical profile for the generation of reactive oxygen species (ROS). In fact this pigment family probably represents the most ef- ficient light collectors and radical generators in nature. Here we describe a recent development of this exciting family of drugs, with particular emphasis on vascular targeted therapy (VTP). [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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