| Autor: |
Schill, Wolf-Bernhard, Comhaire, Frank, Hargreave, Timothy B., Handelsman, D. J., Waites, G. M. H. |
| Zdroj: |
Andrology for the Clinician; 2006, p520-524, 5p |
| Abstrakt: |
Reliable and reversible hormonal contraceptive methods for men, comparable to modern female methods, have been identified, and selected regimens are under active development through the collaboration of andrologists, public sector agencies and pharmaceutical industries. Clinical studies employing prototype drugs have demonstrated that the hormonal approach to switching off spermatogenesis provides contraceptive efficacy and is reversible with short-term safety.No regimen yet achieves consistent azoospermia in all men, although testosterone administration to men in China and Indonesia gets close.Combination regimens involving a second gonadotrophin-suppressing agent, usually a progestin, combined with testosterone achieve close to the ideal of universal suppression of spermatogenesis and contraceptive efficacy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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