Design, Synthesis, and SAR of New Pyrrole-Oxindole Progesterone Receptor Modulators Leading to 5-(7-Fluoro-3,3-dimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-1-methyl-1H-pyrrole-2-carbonitrile (WAY-255348).

Autor: Andrew Fensome, William R. Adams, Andrea L. Adams, Tom J. Berrodin, Jeff Cohen, Christine Huselton, Arthur Illenberger, Jeffrey C. Kern, Valerie A. Hudak, Michael A. Marella, Edward G. Melenski, Casey C. McComas, Cheryl A. Mugford, Ov D. Slayden, Matthew Yudt, Zhiming Zhang, Puwen Zhang, Yuan Zhu, Richard C. Winneker, Jay E. Wrobel
Zdroj: Journal of Medicinal Chemistry; Feb2008, Vol. 51 Issue 6, p1861-1873, 13p
Databáze: Supplemental Index