Structure-Based Design of Novel 2-Amino-6-phenyl-pyrimido[5′,4′:5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as Potent and Orally Active Inhibitors of Lymphocyte Specific Kinase (Lck): Synthesis, SAR, and In Vivo Anti-Inflammatory Activity.
Autor: | Matthew W. Martin, John Newcomb, Joseph J. Nunes, Christina Boucher, Lilly Chai, Linda F. Epstein, Theodore Faust, Sylvia Flores, Paul Gallant, Anu Gore, Yan Gu, Faye Hsieh, Xin Huang, Joseph L. Kim, Scot Middleton, Kurt Morgenstern, Antonio Oliveira-dos-Santos, Vinod F. Patel, David Powers, Paul Rose |
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Zdroj: | Journal of Medicinal Chemistry; Feb2008, Vol. 51 Issue 6, p1637-1648, 12p |
Databáze: | Supplemental Index |
Externí odkaz: |