The Cell-Vessel Architecture Model for the Central Respiratory Chemoreceptor.

Autor: BACK, NATHAN, COHEN, IRUN R., KRITCHEVSKY, DAVID, LAJTHA, ABEL, PAOLETTI, RODOLFO, Hayashida, Yoshiaki, Gonzalez, Constancio, Kondo, Hisatake, OKADA, MASUMASA, KUWANA, SHUN-ICHI, OYAMADA, YOSHITAKA, CHEN, ZIBIN
Zdroj: Arterial Chemoreceptors; 2006, p233-238, 6p
Abstrakt: The group of Loeschcke established that the superficial ventrolateral medulla contains chemosensitive regions (see the reviews [1-3]). Later, the group of Nattie conducted experiments of acetazolamide microinjection that induced local tissue acidosis, and found that the midline region (raphe), nucleus tractus solitarii and locus coeruleus are also chemosensitive (see the review [4]). To map the medullary chemosensitive regions using a more physiological stimulation technique, we microinjected CO2-enriched saline into various regions of the in vivo and in vitro rat medulla, and found that the superficial midline, parapyramidal and ventrolateral regions are chemosensitive [5]. These findings extend other microinjection studies [6,7] that showed only that the superficial ventrolateral medulla is chemosensitive. [ABSTRACT FROM AUTHOR]
Databáze: Supplemental Index