| Autor: |
Mathieu, Daniel, Ratzenhofer-Komenda, B., Niinikoski, J., Hamilton-Farell, M., Muth, Claude, Gröger, Michael, Radermacher, Peter, Speit, Günter |
| Zdroj: |
Handbook on Hyperbaric Medicine; 2006, p147-159, 13p |
| Abstrakt: |
HBO has a DNA-damaging and possibly mutagenic potential. In vitro studies with mammalian cells suggest that HBO-induced oxidative DNA damage mainly leads to gross genetic alterations and chromosome aberrations. Under therapeutic exposure conditions, DNA damage is detected with the comet assay, but mutations and chromosome aberrations are not observed in peripheral blood cells. A very simple and efficient way to avoid HBO-induced DNA damage is to start with a shortened treatment before the standard protocol is applied the following days. Therefore, the hyperbaric community should think about an adaptation of the commonly used treatment protocols [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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