Antifibrinolytic agents in cardiac surgery: current controversies.
| Autor: | Serna, Daniel L., Thourani, Vinod H., Puskas, John D. |
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| Předmět: |
APROTININ
ANTIFIBRINOLYTIC agents CARDIAC surgery CARDIOPULMONARY bypass CARDIOVASCULAR disease diagnosis CARDIOVASCULAR disease related mortality PREVENTION of surgical complications THROMBOEMBOLISM prevention CARDIOVASCULAR diseases CORONARY artery bypass DRUG administration DOSE-effect relationship in pharmacology PROSTHETIC heart valves PROGNOSIS TREATMENT effectiveness PERIOPERATIVE care THERAPEUTICS |
| Zdroj: | Seminars in Thoracic & Cardiovascular Surgery; Mar2005, Vol. 17 Issue 1, p52-58, 7p |
| Abstrakt: | Antifibrinolytic agents play a prominent role in adult cardiac surgery. This article is a review of the modern published experience of antifibrinolytic agent use in adult cardiac surgery. The use of tranexamic acid, epsilon-aminocaproic acid, and aprotinin is examined during primary cardiac surgery, deep hypothermic circulatory arrest, reoperative cardiac surgery, and off-pump coronary artery bypass surgery. In addition, the issues of vein graft patency and hypersensitivity reaction in the presence of antifibrinolytic agents are examined. [Copyright &y& Elsevier] |
| Databáze: | Supplemental Index |
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