Catch-down growth during infancy of children born small (SGA) or appropriate (AGA) for gestational age with short-statured parents.

Autor: Völkl, Thomas M.K., Haas, Bettina, Beier, Christoph, Simm, Diemud, Dörr, Helmuth G.
Zdroj: Journal of Pediatrics; Jun2006, Vol. 148 Issue 6, p747-752, 6p
Abstrakt: Objective: We analyzed postnatal growth in children with familial short stature (FSS) with regard to small (SGA) or appropriate (AGA) for gestational age status at birth. Study design: We studied 96 otherwise healthy short-statured children (58 males; SGA: n = 41, AGA: n = 55). At least one of the parents was short-statured. Cross-sectional data for length/height and weight for the first 4 years of age were collected retrospectively. Results: AGA children had a mean length of 0.09 ± 1.02 standard deviation score (SDS) at birth, −1.57 ± 1.16 SDS after 1 year of age, and −2.36 ± 0.72 SDS after 4 years. SGA children had a mean length of −2.04 ± 1.06 SDS at birth, −2.70 ± 1.12 SDS at 1 year of age, and −3.05±0.86 SDS at 4 years. The loss of length SDS within the first 2 years of life was greater in AGA than in SGA children. SGA children were significantly shorter than AGA children at all of the study points (p <.001). Conclusions: Children with an FSS background born AGA show catch-down growth to their lower familial range during the first 2 years of life. SGA children did not catch up to their AGA peers at any time. [Copyright &y& Elsevier]
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