Hormone replacement therapy and the eye.

Autor: McKinney, Karen A., Buchanan, Trevor A.S.
Zdroj: Journal of the British Menopause Society; 2000, Vol. 6 Issue 1, p15-17, 3p
Abstrakt: Over the past 20 years there has been a revolution in the management of the menopause and the use of hormone replacement therapy (HRT). As the focus on postmenopausal health changes from symptomatic relief to the protective benefits of long-term HRT both ophthalmologists and gynaecologists can expect questions to be asked by their female patients about the influence of HRT on ophthalmic disease. This paper is a review of the current best evidence of effects of HRT on the eye. As oestrogens exert significant influences on the structure and function of ocular structures, we can assume that a reduction in oestrogen levels will have a negative effect on ocular physiology and may play a role in pathological processes in the eye. There is no evidence that HRT is harmful to ocular tissues; case reports point to a beneficial effect of HRT in relation to dry-eye, cataract and macular degeneration in post menopausal women. HRT probably suppresses the formation of cataracts in postmenopausal women and may reduce the incidence of serious retinal disease. [ABSTRACT FROM AUTHOR]
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