| Autor: |
Nunes-Dos-Santos, J, Carvalho-Silva, J, Fernandes-Leite, LD, Carrera, M, Caló-de-Aquino-Xavier, F, Pedreira-Ramalho, LM |
| Zdroj: |
Oral Surgery, Oral Medicine, Oral Pathology & Oral Radiology; Jan2025, Vol. 139 Issue 1, pe24-e24, 1p |
| Abstrakt: |
The Spindle Cell Lipoma (SCL) represents a benign lipomatous neoplasm composed of bland spindle cells amidst a fibromyxoid stroma with rope-like collagen fibers. Its occurrence is rare in the oral cavity. A 47-year-old male patient presented with a solitary, pedunculated, well-circumscribed nodule of 4 cm in the right buccal mucosa covered by usual mucosa. The patient used to bite his buccal mucosa after the lesion development. Microscopically, it showed variable quantities of bland spindle cells and adipocytes throughout in myxoid matrix. In addition, dense rope-like collagen fibers were often. The spindle cells were elongated with oval-shaped nuclei positive for CD34. No true lipoblasts and the usual vasculature of a myxoid liposarcoma or the hyperchromatic cells seen in well-differentiated liposarcomas were absent. Frequently, mast cells positive to toluidine blue were present. Thus, a diagnosis of spindle cell lipoma was rendered. The median size of SCL ranges from 1 to 5 cm, being more common in females. Its differential diagnosis encompasses lipoma, well-differentiated liposarcoma, myxoid liposarcoma, and non-lipomatous tumors rich in spindle cell components. The CD34 positivity in this tumor has supported the spindle cell lipoma diagnosis. This case report deals with an unusual case of spindle cell lipoma displaying an exuberant myxoid matrix occurring in an adult male who acquired a parafunctional habit. Benign and malignant lipomatous tumors arising as nodules should be included in the differential diagnosis of lesions located in the buccal mucosa including traumatic lesions. No relapse has been seen after 12 months of follow-up. [ABSTRACT FROM AUTHOR] |
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