| Abstrakt: |
Researchers from Peking University in Beijing, China, have found that gallic acid (GA) can enhance the graft-versus-leukemia (GVL) effects of T cells without worsening graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT) for acute myeloid leukemia (AML). GA-treated T cells showed increased activation and secretion of cytotoxic cytokines, leading to the apoptosis of AML cells. The study suggests that GA could potentially improve outcomes for patients undergoing HSCT by enhancing GVL effects without exacerbating GVHD. The research was supported by the National Natural Science Foundation of China and has been peer-reviewed. [Extracted from the article] |
