| Abstrakt: |
The research conducted at Karpagam Academy of Higher Education in Tamil Nadu, India, focused on investigating the potential toxic and carcinogenic role of monosodium glutamate (MSG) in male Wistar rats compared to dimethylhydrazine (DMH) in relation to colon cancer development. The study found that high doses of MSG led to a significant decline in survival rate, increased oxidative stress markers, altered organ function, disrupted lipid profiles, and elevated beta-catenin expression in the colon, indicating a potential link to colon cancer development in male Wistar rat models. The study underscores the toxic and carcinogenic role of MSG, particularly in the neoplastic stages of colon cancer in male Wistar rat models. [Extracted from the article] |
