| Autor: |
AtefMikhael, Peter, Naga, Salah Said, Zaki, Sherif Aziz, Mohamed, Amira Hussein |
| Předmět: |
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| Zdroj: |
Alexandria Journal of Medicine; Dec2024, Vol. 60 Issue 1, p76-81, 6p |
| Abstrakt: |
Introduction: Kidney damage in COVID-19 is common and may lead to CKD. Early recognition of progression is mandatory, so there is a need for sensitive markers of kidney damage. Renal functional reserve (RFR) is described as the ability of the kidneys to augment their function in special situations. Aim of Work: Was to assess subclinical renal dysfunction post-COVID-19. Methods: This cross-sectional study investigates 31 patients previously infected with COVID-19 within 2–3 months and 31 healthy subjects with matched age and sex. Assessment of RFR was done by calculating the estimated GFR using the CKD-EPI equation before and 2 hours after 80 g protein load by intravenous infusion. Results: RFR was significantly lower in post-COVID-19 patients (mean of 11.19 ± 4.76) than the control (mean of 25.81 ± 4.42, p < 0.001). Conclusion: Despite preserved eGFR, there is a reduction in RFR, indicating progressive loss of nephron mass post-COVID. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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