| Zdroj: |
Health & Medicine Week; 11/22/2024, p854-854, 1p |
| Abstrakt: |
A preprint abstract discusses the creation of a new mouse model of Alzheimer's disease that does not rely on mutations in MAPT. By introducing humanized tau to AppNL-F/NL-F knock-in mice, researchers were able to observe the initiation of neurofibrillary tau tangle pathology in the absence of such mutations. This model may offer insights into the progression of Alzheimer's disease and the development of potential therapies to prevent tau pathology. The preprint has not yet undergone peer review. [Extracted from the article] |
| Databáze: |
Supplemental Index |
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