New Biology Research from University of Duisburg-Essen Described (Old Passengers as New Drivers: Chromosomal Passenger Proteins Engage in Translesion Synthesis).
| Zdroj: | Genomics & Genetics Weekly; 11/22/2024, p889-889, 1p |
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| Abstrakt: | The University of Duisburg-Essen conducted research on the role of chromosomal passenger proteins in DNA damage response and replication processes. The study found that Survivin and CPC proteins play a crucial role in managing damage-induced replication stress and transitioning from stalled replication forks to translesion synthesis. This research sheds light on the potential implications for therapy resistance and maintaining genomic integrity, particularly in tumors. The study was supported by the German Research Foundation Dfg and published in the journal Cells. [Extracted from the article] |
| Databáze: | Supplemental Index |
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