| Abstrakt: |
Researchers from Nanchang University have explored the relationship between keratin 18 (K18) and epithelial-derived tumors, highlighting its potential as a diagnostic and prognostic marker in tumorigenesis. K18, a non-hair keratin, is widely expressed in simple epithelial tissues and plays crucial roles in biological regulation, such as anti-apoptosis and cell cycle progression. The study emphasizes the importance of K18 in various epithelial-derived tumors like adenocarcinomas and suggests its application in diagnosing tumors and predicting prognosis. The research provides insights into the interactions of K18 with related proteins in tumorigenesis, focusing on examples from lung, breast, liver, and gastrointestinal cancers. [Extracted from the article] |
