| Abstrakt: |
A recent report from "Alexandru Ioan Cuza" University of Iasi in Romania discusses the use of tumor-on-chip platforms for modeling breast cancer. These platforms, including breast cancer-on-chip, breast cancer liquid biopsy-on-chip, and breast cancer metastasis-on-chip models, are able to replicate the mechanisms and events involved in breast cancer progression. They can be used to study cell proliferation, communication between cells, stromal activation, invasion, migration, and immune escape of cancer cells. Additionally, these platforms can be used to assess the efficacy and toxicity of chemotherapeutic drugs and nutraceuticals. The integration of tumor-on-chip platforms with proteomics-based approaches may lead to the discovery of novel biomarkers for breast cancer. The research also highlights the potential of multi-organ-on-chip systems for personalized and precision medicine. [Extracted from the article] |
