Abstrakt: |
Researchers from the Koneru Lakshmaiah Education Foundation in Vaddeswaram, India have developed nanosponge formulations of the anti-hyperlipidemic drug Rosuvastatin (ROS) to increase its bioavailability. The researchers used the Quality by Design (QbD) method and Central Composite Design (CCD) to design the formulations, which were assessed based on various parameters including particle size, drug release, and drug-excipient interaction. The optimized formulation (RF16) showed a 2-fold enhancement in the bioavailability of ROS compared to the pure drug. This research has been published in the Indian Journal of Pharmaceutical Education and Research. [Extracted from the article] |