Data from Yangzhou University Provide New Insights into Cancer (Design Strategy of Cuminaldehyde/b-cyclodextrin Polymer Inclusion Complex With Superior Antibacterial and Anti-cancer Ability).

Zdroj: Cancer Weekly; 9/24/2024, p114-114, 1p
Abstrakt: Researchers from Yangzhou University in Jiangsu, China have developed a new method to improve the water solubility and stability of cuminaldehyde (CUM), a bioactive compound with anti-inflammatory, antioxidant, antitumor, and antibacterial effects. They used a cyclodextrin polymer to encapsulate CUM, resulting in a highly water-soluble complex called CUM-0-CDP. This complex demonstrated superior antibacterial ability and inhibited the proliferation and migration of HepG2 cells, indicating promising anti-cancer potential. The successful design of this inclusion complex offers a new approach for delivering natural drug molecules with low water solubility. [Extracted from the article]
Databáze: Supplemental Index