| Zdroj: |
Drug Week; 8/30/2024, p2542-2542, 1p |
| Abstrakt: |
A recent report from Shanghai Jiao Tong University School of Medicine discusses the structure and function of somatostatin and its receptors in endocrinology. The researchers highlight the use of somatostatin analogs as important drugs for the treatment of acromegaly and as molecules for radiation therapy and imaging of neuroendocrine tumors. The study utilized cryogenic electron microscopy and protein structure prediction to determine the three-dimensional structures of somatostatin receptors. The findings provide insights into the ligand binding pocket and the potential for novel structure-based therapies. [Extracted from the article] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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