| Autor: |
Young, Rebecca N., Lahiri, Rashmi |
| Zdroj: |
Diagnostic Histopathology; Aug2024, Vol. 30 Issue 8, p469-472, 4p |
| Abstrakt: |
Angioimmunoblastic T-cell lymphoma was reclassified a subtype of nodal T-follicular helper cell lymphoma (nTFHL-AI) in the 5th Edition of the World Health Organization Classification of Haematolymphoid Tumours. It is now grouped with related entities upon recent discovery of a shared T-follicular helper (TFH) cell origin. Numerous studies attest to the many peculiar presentations that impede recognition of the disease. Surgical biopsy is often required to secure a diagnosis though is rarely the first-line intervention. Delayed or missed diagnosis has a high price. Advanced stage of disease at presentation is common and rates of relapse are high. There is an unmet need for earlier detection and improved outcomes. Here we present a case which showed some quintessential clinicopathologic features of nTFHL-AI, and an approach to discerning these is discussed. [ABSTRACT FROM AUTHOR] |
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