Abstrakt: |
A study conducted at the Almazov National Medical Research Centre explored the reactions to novelty in the rat brain during dissociative anesthesia. The researchers used an epidural 32-electrode array to record mismatch negativity-like waves from the somatosensory cortex. They found that the amplitude of the tonic component of the waves increased with deeper levels of sedation, while gamma power decreased and delta power and the frequency of down-states increased. The study suggests that the slow mismatch negativity-like wave observed during anesthesia reflects the brain's tendency to respond with delta waves, K-complexes, and down-states. [Extracted from the article] |