The effects of dietary nitrate ingestion on physical performance tests in 50–65 years old postmenopausal women: A pilot randomized, double-blind, placebo-controlled, and crossover study.

Autor: Benjamim, Cicero Jonas R., Lopes da Silva, Leonardo Santos, da Silva Gonçalves, Leonardo, Tasinafo Júnior, Márcio Fernando, Spellanzon, Bruno, Rebelo, Macario Arosti, Tanus-Santos, José E., Bueno Júnior, Carlos Roberto
Zdroj: Clinical Nutrition; Jul2024, Vol. 43 Issue 7, p1642-1646, 5p
Abstrakt: The post-menopausal period represents a noteworthy stage in a woman's life characterized by hormonal shifts that can influence diverse biological processes encompassing energy metabolism and physical performance. NO 3 − effects on physical performance in 50–65 years old postmenopausal women after short-term supplementation remain unknown. This is a randomized, double-blind, placebo-controlled, crossover study. After two sessions in non-consecutive days of familiarization tests, fifteen post-menopausal women aged between 50 and 65 were enrolled in this study. The trial consisted of two eight-day arms: a) NO 3 − −70 mL of beetroot juice (BRJ) with ˜400 mg of NO 3 −, and b) placebo (PLA) −70 mL of BRJ NO 3 − depleted. Both interventions were obtained from the same manufacturer's product, presenting the same organoleptic properties. After this period, five physical performance tests (handgrip strength, arm curl, sit-to-stand, agility and dynamic balance and 6-min walk test (6MWT)) were applied. Fourteen participants completed all experimental protocols, including a minimum seven-day washout period between protocols. NO 2 − plasma concentrations were consistently elevated in the NO 3 − condition at 0.41 (0.40) μM compared to the PLA at 0.18 (0.18) μM (p < 0.001). The 6MWT showed higher values in BRJ with NO 3 − condition (19.6 m [95%CI: 1.33 to 37.88]; p = 0.038), while the other physical performance tests did not show significant difference between conditions (p > 0.05). Our findings suggest benefits in the physical performance of activities with longer durations, indicating that the adaptation caused by ingestion of NO 3 − may be related to the cardiorespiratory capacity. NO 2 −/NO 3 − = nitrite/nitrate; 6MWT(M) = 6-min walk test; PLA = placebo. [Display omitted] [ABSTRACT FROM AUTHOR]
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