| Autor: |
Tung, Ninh Khac Thanh, Lan, Hoang Thi Tuyet, Nga, Tran Thuy, Thi Mai, Nguyen, Thao, Vu Mai, Dung, Nguyen Viet, Dat, Nguyen Tien, Nhiem, Nguyen Xuan, Tan, Nguyen Bao, Kim, Hyung Min, Kang, Jong Seong |
| Zdroj: |
Phytochemistry Letters; Jun2024, Vol. 61, p166-170, 5p |
| Abstrakt: |
By combining chromatography methods, three new flavonoid glycosides, kaempferol 3- O - α -L-rhamnopyranosyl-(1→2)- β -D-glucopyranosyl-(1→2)- α -L-rhamnopyranoside (1), kaempferol 3- O- (4-acetyl)- α -L-rhamnopyranosyl-(1→2)- β -D-glucopyranosyl-(1→2)- α -L-rhamnopyranoside (2), and (2 R ,3 S) 5,7,4′-tetrahydroxyflavanonol 3- O- (4-acetyl)- α -L-rhamnopyranosyl-(1→2)- β -D-glucopyranosyl-(1→2)- α -L-rhamnopyranoside (3) as well as three known compounds, chrysandroside A (4), p -hydroxybenzaldehyde (5), and p -hydroxybenzoic acid (6) were isolated from the leaves of Camellia phanii Hakoda & Ninh. Their structure was elucidated by 1D and 2D-NMR spectra and compared to previously published in literature. In addition, all compounds were evaluated for their ability to inhibit α -glucosidase activity. As the results, flavonoid glycosides 1 - 3 inhibited α -glucosidase activity with IC 50 values of 276.8 ± 19.4, 258.9 ± 24.3, and 341.4 ± 25.6 µM; phenolics (5 and 6) inhibited α -glucosidase activity with IC 50 values of 295.5 ± 15.1 and 217.4 ± 23.6 µM, respectively. [Display omitted] • Three new flavonoid glycosides were isolated from the leaves of Camellia phanii. • The structures were successfully determined by spectroscopic methods. • Flavonoid glycosides 1 - 3 inhibited α -glucosidase activity. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
Full Text from ScienceDirect