| Autor: |
O'Donnell, Carolyn, Demler, Tammie Lee, Trigoboff, Eileen, Lee, Claudia |
| Předmět: |
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| Zdroj: |
Innovations in Clinical Neuroscience; Apr-Jun2024, Vol. 21 Issue 4-6, p27-30, 4p |
| Abstrakt: |
Introduction: Well-known adverse events of antipsychotics are movement disorders, or extrapyramidal symptoms, such as drug- induced parkinsonism and tardive dyskinesia. Objective: With new evidence suggesting a link between low high-density lipoprotein cholesterol (HDL-C) and risk of Parkinson's disease, this study sought to investigate if that link also translated to patients taking antipsychotics with low HDL-C and an increased risk for developing a movement disorder. Design: Adult patients (n=89) at an inpatient state psychiatric facility taking at least one antipsychotic with at least one HDL-C level were assessed for signs of a movement disorder through their history and physical, progress notes, and Abnormal Involuntary Movement Scale (AIMS) score. Results: There was no statistical significance when comparing a patient's movement disorder, AIMS scores, and HDL-C levels to suggest that the HDL-C level influenced a patient's movement disorder. Conclusion: This study did not show a correlation between HDL-C levels and a patient's risk of developing a movement disorder while taking an antipsychotic. [ABSTRACT FROM AUTHOR] |
| Databáze: |
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